(DOWNLOAD) "Platelet-Activating Factor (PAF) Receptor-Binding Antagonist Activity of Malaysian Medicinal Plants." by Phytomedicine: International Journal of Phytotherapy & Phytopharmacology # eBook PDF Kindle ePub Free
eBook details
- Title: Platelet-Activating Factor (PAF) Receptor-Binding Antagonist Activity of Malaysian Medicinal Plants.
- Author : Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
- Release Date : January 01, 2005
- Genre: Life Sciences,Books,Science & Nature,
- Pages : * pages
- Size : 203 KB
Description
Abstract Forty-nine methanol extracts of 37 species of Malaysian medicinal plants were investigated for their inhibitory effects on platelet-activating factor (PAF) binding to rabbit platelets, using [.sup.3]H-PAF as a ligand. Among them, the extracts of six Zingiberaceae species (Alpinia galanga Swartz., Boesenbergia pandurata Roxb., Curcuma ochorrhiza Val., C. aeruginosa Roxb., Zingiber officinale Rosc. and Z. zerumbet Koenig.), two Cinnamomum species (C. altissimum Kosterm. and C. pubescens Kochummen.), Goniothalamus malayanus Hook. f. Momordica charantia Linn. and Piper aduncum L. are potential sources of new PAF antagonists, as they showed significant inhibitory effects with I[C.sub.50] values ranging from 1.2 to 18.4 [micro]g m[l.sup.-1].